Pubmed-entry ::= {
  pmid 21442819,
  medent {
    em std {
      year 2011,
      month 3,
      day 28
    },
    cit {
      title {
        name "[Effects of medicated thread moxibustion of Zhuang medicine on
 sex hormone in ovariectomized rabbits]."
      },
      authors {
        names ml {
          "Yang MC",
          "Han LJ",
          "Li J",
          "Fang G",
          "Xiao XQ"
        },
        affil str "Ruikang Clinical Medical College Affiliated to Guangxi
 College of TCM, Nanning 530001, China. Ymchun2004@yahoo.com.cn"
      },
      from journal {
        title {
          iso-jta "Zhongguo Zhen Jiu",
          ml-jta "Zhongguo Zhen Jiu",
          issn "0255-2930",
          name "Zhongguo zhen jiu = Chinese acupuncture & moxibustion"
        },
        imp {
          date std {
            year 2011,
            month 2
          },
          volume "31",
          issue "2",
          pages "145-148",
          language "chi",
          pubstatus ppublish,
          history {
            {
              pubstatus other,
              date std {
                year 2011,
                month 3,
                day 30,
                hour 6,
                minute 0
              }
            },
            {
              pubstatus pubmed,
              date std {
                year 2011,
                month 3,
                day 30,
                hour 6,
                minute 0
              }
            },
            {
              pubstatus medline,
              date std {
                year 2011,
                month 4,
                day 27,
                hour 6,
                minute 0
              }
            }
          }
        }
      },
      ids {
        pubmed 21442819
      }
    },
    abstract "OBJECTIVE: To explore the mechanism of medicated thread
 moxibustion of Zhuang medicine (MTMZ) in treating perimenopausal period
 syndrome. METHODS: Thirty rabbits were randomly divided into a normal group,
 a model group, a medicated thread group, a no-medicated thread group and a
 sham operation group, 6 cases in each group. The model of perimenopausal
 period syndrome was established by ovariectomizing the ovary. The medicated
 thread group was treated with MTMZ at ""Qizhou"" acupoint (Extra), ""Xiaguany
uan""(Extra), ""Shenshu"" (BL 23) and ""Pishu"" (BL 20), etc., once each day
 for 4 weeks. The no-medicated thread group was treated with no-medicated
 thread moxibustion at the same acupoints, and there is no treatment in the
 other groups. The changes of hormone level in each group before and after the
 treatment were observed. RESULTS: After ovariectomizing the ovary, the serum
 estradiol (E2) in the model group [(308.33 +/- 12.58) pmol/L], the medicated
 thread group [(304.96 +/- 13.85) pmol/L] and the no-medicated thread group
 [(303.43 +/- 10.57) pmol/L] were lower than that in the normal group [(478.09
 +/- 12.23) pmol/L] and the sham operation group [(488.05 +/- 11.45) pmol/L]
 (all P < 0.01). After treatment, the E2 level in medicated thread group
 [(338.92 +/- 11.23) pmol/L] was higher than before (P < 0.01) and that in the
 model group [(300.53 +/- 13.68) pmol/L] and the no-medicated thread group
 [(309.74 +/- 13.59) pmol/L] (both P < 0.01), and the serum follicle
 stimulating hormone [FSH, (58.90 +/- 5.29) U/L] and luteinizing hormone [LH,
 (64.65 +/- 5.23) U/L] were lower than those in the model group [(65.41 +/-
 5.19) U/L], [(71.85 +/- 5.30) U/L] (both P < 0.05). CONCLUSION: MTMZ can
 increase the serum E2 and reduce the serum FSH and LH in ovariectomized
 rabbits, and this may be one of the mechanisms of MTMZ for treatment of
 perimenopausal period syndrome.",
    mesh {
      {
        term "Animals"
      },
      {
        term "Estradiol",
        qual {
          {
            mp TRUE,
            subh "blood"
          }
        }
      },
      {
        term "Female"
      },
      {
        term "Follicle Stimulating Hormone",
        qual {
          {
            subh "blood"
          }
        }
      },
      {
        term "Humans"
      },
      {
        term "Luteinizing Hormone",
        qual {
          {
            subh "blood"
          }
        }
      },
      {
        mp TRUE,
        term "Medicine, Chinese Traditional"
      },
      {
        mp TRUE,
        term "Menopause"
      },
      {
        term "Moxibustion",
        qual {
          {
            mp TRUE,
            subh "methods"
          }
        }
      },
      {
        term "Ovariectomy"
      },
      {
        term "Rabbits"
      },
      {
        term "Random Allocation"
      }
    },
    substance {
      {
        type cas,
        cit "50-28-2",
        name "Estradiol"
      },
      {
        type cas,
        cit "9002-67-9",
        name "Luteinizing Hormone"
      },
      {
        type cas,
        cit "9002-68-0",
        name "Follicle Stimulating Hormone"
      }
    },
    pmid 21442819,
    pub-type {
      "English Abstract",
      "Journal Article",
      "Research Support, Non-U.S. Gov't"
    },
    status medline
  }
}

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