Pubmed-entry ::= {
  pmid 7782085,
  medent {
    em std {
      year 1995,
      month 7,
      day 20
    },
    cit {
      title {
        name "Molecular cloning of the microfibrillar protein MFAP3 and
 assignment of the gene to human chromosome 5q32-q33.2."
      },
      authors {
        names ml {
          "Abrams WR",
          "Ma RI",
          "Kucich U",
          "Bashir MM",
          "Decker S",
          "Tsipouras P",
          "McPherson JD",
          "Wasmuth JJ",
          "Rosenbloom J"
        },
        affil str "Department of Anatomy and Histology, School of Dental
 Medicine, University of Pennsylvania, Philadelphia 19104, USA."
      },
      from journal {
        title {
          iso-jta "Genomics",
          ml-jta "Genomics",
          issn "0888-7543",
          name "Genomics"
        },
        imp {
          date std {
            year 1995,
            month 3,
            day 1
          },
          volume "26",
          issue "1",
          pages "47-54",
          language "eng",
          pubstatus ppublish,
          history {
            {
              pubstatus pubmed,
              date std {
                year 1995,
                month 3,
                day 1
              }
            },
            {
              pubstatus medline,
              date std {
                year 1995,
                month 3,
                day 1,
                hour 0,
                minute 1
              }
            },
            {
              pubstatus other,
              date std {
                year 1995,
                month 3,
                day 1,
                hour 0,
                minute 0
              }
            }
          }
        }
      },
      ids {
        pubmed 7782085,
        pii "0888-7543(95)80081-V"
      }
    },
    abstract "Microfibrils having a diameter of 10-12 nm, found either in
 association with elastin or independently, are an important component of the
 extracellular matrix of many tissues, but characterization of these
 microfibrils is incomplete. To further our understanding of the gene
 structure of proteins composing the microfibrils and to identify their
 chromosomal location, we have cloned and characterized another microfibril
 protein, designated microfibril-associated protein-3 (MFAP3). The human gene
 encoding MFAP3 has a very simple structure, containing only two translated
 exons encoding a protein of 362 amino acids. Monospecific antibodies prepared
 against the recombinantly expressed protein reacted with the microfibrils
 found in ocular zonules. MFAP3 does not appear to share homology with any
 other known protein. The gene was found to be located on chromosome
 5q32-q33.2, near the locus 5q21-q31 reported for the fibrillin gene, FBN2,
 which has been linked to congenital contractural arachnodactyly. MFAP3 is a
 candidate gene for heritable diseases affecting microfibrils.",
    mesh {
      {
        term "Amino Acid Sequence"
      },
      {
        term "Animals"
      },
      {
        term "Base Sequence"
      },
      {
        term "Blotting, Northern"
      },
      {
        term "Blotting, Western"
      },
      {
        term "Cattle"
      },
      {
        term "Chromosome Mapping"
      },
      {
        term "Chromosomes, Human, Pair 5",
        qual {
          {
            mp TRUE,
            subh "genetics"
          }
        }
      },
      {
        term "Cloning, Molecular"
      },
      {
        term "Contractile Proteins",
        qual {
          {
            subh "biosynthesis"
          },
          {
            mp TRUE,
            subh "genetics"
          }
        }
      },
      {
        term "Cricetinae"
      },
      {
        term "Extracellular Matrix Proteins",
        qual {
          {
            subh "genetics"
          }
        }
      },
      {
        term "Female"
      },
      {
        term "Humans"
      },
      {
        term "Molecular Sequence Data"
      },
      {
        term "Polymerase Chain Reaction"
      },
      {
        term "Rabbits"
      },
      {
        term "Recombinant Fusion Proteins"
      },
      {
        term "Sequence Homology, Nucleic Acid"
      }
    },
    substance {
      {
        type nameonly,
        name "Contractile Proteins"
      },
      {
        type nameonly,
        name "Extracellular Matrix Proteins"
      },
      {
        type nameonly,
        name "Recombinant Fusion Proteins"
      },
      {
        type nameonly,
        name "microfibrillar protein"
      },
      {
        type cas,
        cit "165446-76-4",
        name "MFAP3 protein, human"
      }
    },
    xref {
      {
        type genbank,
        cit "L35250"
      },
      {
        type genbank,
        cit "L35251"
      }
    },
    idnum {
      "AR41474/AR/NIAMS NIH HHS",
      "HG00834/HG/NHGRI NIH HHS"
    },
    pmid 7782085,
    pub-type {
      "Journal Article",
      "Research Support, U.S. Gov't, P.H.S."
    },
    status medline
  }
}

Other elisa kits Products